VITAMINS, HERBAL & ANTI-AGING

Stress Relief

:: Improves mood and alleviate depression (Rhodiola rosea)
:: Supports the immune system (increases CD3 and CD4 levels)
:: Has anti-inflammatory activity (decreased cortisol : DHEA ratio)
:: Assists with glutathione production

Ashwagandha contains flavonoids and many active ingredients of the withanolide class (antioxidant)

Rhodiola rosea has been categorized as an adaptogen due to its observed ability to increase resistance to a variety of chemical, biological, and physical stressors. An adaptogen is an agent that allows an organism to counteract adverse physical, chemical, or biological stressors by generating non-specific resistance.

Rhodiola rosea is included among a class of plant derivatives called adaptogens which differ from chemical stimulants, such as nicotine, and do not have the same physiological effects. In Russia and Scandinavia, Rhodiola rosea, also known as golden root, has been used for centuries to cope with the cold Siberian climate and stressful life. Such effects were provided evidence in rats in which Rhodiola effectively prevented stress-induced changes in appetite, physical activity, weight gain and the estrus cycle. Rhodiola rosea contains many actives including rosavin, rosarin, rosin, salidroside, proanthocyanidins, quercetin, gallic acid, chlorogenic acid and kaempferol. Rhodiola rosea’s effects potentially are related to optimizing serotonin and dopamine levels due to monoamine oxidase inhibition and its influence on opioid peptides such as betaendorphins, although these specific neurochemical mechanisms have not been clearly documented with scientific studies.

Recommended Use

As a dietary supplement, take 1-2 capsules per day between, or 30 minutes prior to a meal. As with most herbal blends, it is advisable to give a break of one week after six weeks of this product’s use.
 

Condition Specific Information

Subjecting humans and animals to a period of stress produces characteristic changes in several hormones and parameters associated with the central nervous system (CNS) and the hypothalamic-pituitary-adrenal axis (HPA). HPA changes include an increase in cortisol, a reduced sensitivity of the HPA to feedback down-regulation, and a disruption in the circadian rhythm of cortisol secretion. CNS changes include the stress-induced depletion of catecholamine neurotransmitters such as norepinephrine and dopamine; an acute increase in beta-endorphin levels is also observed under stressful conditions.

To successfully combat stress and stressful situations, adaptation is required. Adaptation might be best thought of as the ability to be exposed to a stressor, while responding with either decreased or no characteristic hormonal perturbations. Adaptation also implies being prepared to and capable of rapidly reassuming homeostasis after the stressor is withdrawn. As an example, a well-trained athlete can participate in an event that would induce a large HPA perturbation (stress response) in a sedentary person, and yet the athlete will be relatively unaffected. This is a result of adaptation that has occurred during the athlete’s training process. Additionally, if athletes are exposed to stressors they were not trained for, hormonal perturbations characteristic of a stress response would be expected; however, this response might not be as great as that found in less fit individuals. Furthermore, after the stress ended, their physiology would be expected to re-establish homeostasis rapidly. This is a result of non-specific resistance to stress gained by virtue of a training-induced higher level of fitness.

The utility of plant adaptogens is analogous to the training an athlete undergoes in order to prepare for competition. Plant adaptogens cause our physiology to begin the adaptation process to stress. When a stressful situation occurs, consuming adaptogens generates a degree of generalized adaptation (or non-specific resistance) that allows our physiology to handle the stressful situation in a more resourceful manner.

As an example of this process, Rhodiola rosea administration promotes a moderate increase in the amount of serum immunoreactive beta-endorphin in rats under basal conditions. This moderate increase is similar to that found when rats are adapted to exercise. When Rhodiola rosea-treated rats were subjected to a 4-hour period of non-specific stress, the expected elevation in beta-endorphin was either not observed or substantially decreased. Consequently, the characteristic perturbations of the HPA were decreased or totally prevented. In these rats administration of Rhodiola rosea appears to have generated non-specific resistance and prepared the rats to respond more appropriately to the eventual stressful situation.

 

Precautions and Contra-indications

Not to be taken by pregnant or lactating woman. Seek advice from your healthcare practitioner while taking prescription medicine or diagnosed with an illness or disease. This product is a dietary supplement and is not intended to diagnose, treat, cure or prevent any disease. Store below 25ºC in a cool, dry place and keep out of reach of children.

   

Supplement Facts

Amount per Serving: 2 Capsules

Ingredients
Amount per serving
Role of Ingredients
Alpha lipoic acid
100mg
Antioxidant; co-factor for a number of enzymes involved in converting fat and sugar to energy; assists with
glutathione production
Rhodiola Rosea
200mg
Adaptogen - improves mood and alleviate depression
Ashwagandha root/leaf extract
(8% withanolides)
225mg
A general tonic and adaptogen, helping the body adapt to stress; possess antioxidant activity as well as an ability to support a healthy immune system. It has anti-anxiety effects due to its GABA-like activity
Beta-sitosterol
70mg
Supports the immune system (increases CD3 and CD4 levels); has anti-inflammatory activity (decreased cortisol : DHEA ratio)
B-sitosterol glucosides (sterolins)
0.7mg
Supports the immune system (increases CD3 and CD4 levels); has anti-inflammatory activity (decreased cortisol : DHEA ratio)
 
 
Packaging: Available in 60 Capsules